Berberine
The alkaloid the formula leads with, studied for how cells take glucose in.
The panel
Fourteen ingredients inside a 500 mg proprietary formulation. A page apiece, each carrying its own evidence grade.
The alkaloid the formula leads with, studied for how cells take glucose in.
A kitchen spice with the longest run of human trials in this category.
Called gurmar, sugar destroyer, for what it does to sweet taste.
A Philippine tree leaf carrying corosolic acid, drunk as tea for generations.
A gourd eaten daily across Asia, bitter enough that nobody eats it by mistake.
A compound your own mitochondria make, active in both water and fat.
A trace mineral with a published intake figure and a settled nutrition role.
Vitamin B7, without which five carboxylase enzymes simply stop.
Fed to silkworms for centuries, and carrying a molecule shaped enough like sugar to matter.
The rhizome behind curry colour and one of the most studied plants alive.
Not a berry but a cone, and the reason gin tastes the way it does.
A root crop farmed higher up a mountain than almost any other food plant.
A dried fruit from Ningxia, unusually rich in the carotenoid zeaxanthin.
Fifty times sweeter than sugar by weight, and the one item here with a ceiling.
Outside the blend: a vegetable cellulose shell, rice flour and magnesium stearate.
Order GlycoAidSupplement labels print ingredients in descending order by weight. On this bottle that means Berberine carries more of the 500 mg than anything below it and licorice root carries the least. That is the whole yield of the ordering rule. It cannot say whether the first name is 300 mg or 60 mg.
The rest of this page tries to turn that limit into something usable instead of talking past it.
Every panel page carries one of four grades. They describe the research behind the ingredient, not behind this product, and they are never averaged into a single number anywhere on this site.
| Ingredient | Grade | What that means |
|---|---|---|
| Berberine | Large | Many controlled human trials |
| Cinnamon Bark | Large | Many controlled human trials |
| Gymnema Sylvestre | Moderate | Several small human studies |
| Banaba Leaf | Moderate | Several small human studies |
| Bitter Melon | Moderate | Several small human studies |
| Alpha-Lipoic Acid | Large | Many controlled human trials |
| Chromium | Large | Many controlled human trials |
| Biotin | Settled | An established nutritional role |
| White Mulberry Leaf | Moderate | Several small human studies |
| Turmeric Root | Large | Many controlled human trials |
| Juniper Berry | Small | Long traditional use, limited modern trials |
| Maca Root | Small | Long traditional use, limited modern trials |
| Goji Berry | Small | Long traditional use, limited modern trials |
| Licorice Root | Moderate | Several small human studies |
Grouped by what they are actually doing, the panel reads far more clearly. Glucose uptake and insulin sensitivity: Berberine, alpha-lipoic acid and Chromium. Carbohydrate absorption and sweet taste: gymnema, white mulberry and banaba leaf. Antioxidant support: turmeric, goji berry and again alpha-lipoic acid. Traditional-use items: maca, juniper and licorice, with bitter melon and cinnamon bark alongside them.
Two names come up more than the rest. Berberine is printed first, so it carries the largest share of the blend, and chromium is the one item with an established nutritional role rather than a contested one.
Research on these ingredients was done at specific doses, mostly one ingredient at a time. A proprietary blend declares one combined weight, so no trial maps onto this capsule directly. That is the single most important thing to understand about this label, which is why it sits on the front page rather than in a footnote.

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A 500 mg proprietary formulation taken once a day with a meal, and sixty days to decide what you make of it.